Philippe cassard biography of martin luther
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Ionarts
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High endothelial venules (HEVs) in immunity, inflammation and cancer
Abstract
High endothelial venules (HEVs) are specialized blood vessels mediating lymphocyte trafficking to lymph nodes (LNs) and other secondary lymphoid organs. By supporting high levels of lymphocyte extravasation from the blood, HEVs play an essential role in lymphocyte recirculation and immune surveillance for utländsk invaders (bacterial and viral infections) and alterations in the body’s own cells (neoantigens in cancer). The HEV network expands during inflammation in immune-stimulated LNs and is profoundly remodeled in metastatic and tumor-draining LNs. HEV-like blood vessels expressing high levels of the HEV-specific sulfated MECA-79 antigens are induced in non-lymphoid tissues at sites of chronic inflammation in many human inflammatory and allergic diseases, including rheumatoid arthritis, Crohn’s disease, allergic rhinitis and asthma. Such vessels are believed to contribute to the amplification and maint
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Clifden Arts Festival In partnership with Cruit Éireann Harp Ireland presents Summer Harps at Clifden
Experience some of Ireland’s finest harpers in concert, with Seamus Ó Flatharta, Úna Ní Fhlannagáin and Lynn Saoirse, as they perform an eclectic and entertaining mix of harp music celebrating our national emblem.
Úna Ní Fhlannagáin is an award-winning harper-composer and singer from Co. Galway, Ireland. She is rooted in diverse musical influences such as the dance music tradition of North Clare, the sean-nós singing style of Maigh Seola, the American post-minimalists and free jazz.
Séamus Ó Flatharta is a multi-instrumentalist, singer and dancer from Áird Mhór in the heart of Connemara. Since the age of 16, he has been making waves in the fields of music, song and dance, performing in China, The USA, Canada, The United Kingdom and throughout mainland Europe.
Lynn Saoirse has been living near Clifden for most of the last 36 years. She has performed widely: throughout Europe and